Search on: IDURONATE SULFATE SULFATASE 
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Descriptor English:   Iduronate Sulfatase 
Descriptor Spanish:   Iduronato Sulfatasa 
Descriptor Portuguese:   Iduronato Sulfatase 
Synonyms English:   Iduronate Sulfate Sulfatase
Corrective Factor, Hunter
Factor, Hunter Corrective
Sulfatase, Iduronate
Sulfatase, Iduronate Sulfate
Sulfatase, Sulfoiduronate
Sulfate Sulfatase, Iduronate
Sulfohydrolase, Iduronatesulfate
Hunter Corrective Factor
Iduronatesulfate Sulfohydrolase
Sulfoiduronate Sulfatase  
Tree Number:   D08.811.277.352.827.500
Definition English:   An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13. 
Entry Combination - descr/qualif English:   Iduronate Sulfatase/deficiency use Mucopolysaccharidosis II
 
See Related English:   Mucopolysaccharidosis II
 
History Note English:   91(76); was see under SULFATASES 1976-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   7393 
Unique Identifier:   D007066 

Occurrence in VHL: 		 

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